Simulation and Optimization Models for Integrated Production Planning

Integrated planning for blood platelet production: a robust optimization approach

Perishability of blood products as well as uncertainty in demand amounts complicate the management of blood supply for blood centers. This paper addresses a mixed-integer linear programming model for blood platelets production planning while integrating the processes of blood collection as well as production/testing, inventory control and distribution. Whole blood-derived production methods for...

integrated planning for blood platelet production: a robust optimization approach

perishability of blood products as well as uncertainty in demand amounts complicate the management of blood supply for blood centers. this paper addresses a mixed-integer linear programming model for blood platelets production planning while integrating the processes of blood collection as well as production/testing, inventory control and distribution. whole blood-derived production methods for...

Simulation-based Ga Optimization for Production Planning

Effective production planning requires models that are capable of accounting for the complexity and uncertainty intrinsic to manufacturing systems. While the identification of a globally optimal plan is desirable, a more important requirement is the ability of a model to produce production plans that are sufficiently realistic to be implemented in practice and are robust to perturbations in the...

Novel Models and Algorithms for Integrated Production Planning and Scheduling

Models for Integrated Production Planning and Order Selection

The vast body of literature on dynamic requirements planning problems in make-to-order production systems assumes that demands in all periods are predefined. In many practical contexts, however, a producer has discretion to accept or deny production orders during the production planning process. That is, given a set of orders for production at a single stage in a set of time periods, along with...